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Fully-Automated Cryopreservation System for the field of Regenerative Medicine

To accelerate research and development in the field of regenerative medicine with human cells, a safe and reliable cell cryopreservation process is critical.

"Ultra low temperature" with liquid nitrogen stops all biological action.

Post-thaw human iPS cells (cell line of Kyoto University)

Post-thaw human iPS cells (cell line of Kyoto University)

The cryopreservation of biological samples with liquid nitrogen is considered the optimal method to stop all biological action. Its practical use started in the livestock industry around 1970, and later expanded into the fields of basic research.

We have already sold about 90,000 cryopreservation containers and have a domestic market share of about 50%.
We have also delivered about 100 units of "Cell Bank Systems" used for the unified management of cryopreservation containers. They are used in some of the major research institutions including RIKEN and the University of Tokyo.

"CryoLibrary® Advance" realizes the highly efficient cryopreservation of a large volume of biological samples.

 CryoLibrary® Advance

CryoLibrary® Advance

In 2008, Dr. Yamanaka at Kyoto University (currently Director of the Center for iPS Cell Research and Application) discovered iPS cells. There is an increasing number of research and development activities in the field of regenerative medicine with human cells.

For the practical realization of regenerative medicine, it is essential to establish technologies for the reliable management of high-quality cultured cells and efficient cryopreservation of a large volume of them.

Leveraging our strength as the only manufacturer of cryopreservation containers in Japan, we launched the fully-automated cryopreservation system "CryoLibrary®" in 2009, that allows for the reliable management of biological samples such as cells. The system has received a favorable reception since launch.

"CryoLibrary® Advance", launched in March 2015, supports storage or delivery in units of both vials and vial boxes. It can accommodate more than 3 times that of the conventional model.

The degree of evaporation of liquid nitrogen has been reduced to 1/2 or less. It can maintain a temperature below -150℃ for 20 days or longer.

In addition, the high performance image processing cameras can instantly read the 2D barcodes on the bottoms of vials inside a vial box for accelerated handling.

We will continue to develop technologies and improve our equipment to meet the needs of various fields such as the regenerative medicine and bio-pharmaceutical fields.